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By decreasing the desire for food and other substances like alcohol, cannabis, opioids, and cigarettes, these medications might also alter sexual desire
Shifts in energy availability or metabolic health modulate hypothalamic signaling and subsequent reproductive hormones
What Users Report Off-Label Men who have used PT-141 off-label commonly describe: Stronger response to sexual cues Better erections when low desire was the missing link Improvement in mixed ED, where both psychological and vascular factors are involved These experiences match what researchers have seen: PT-141 supports both libido and erectile performance, making it helpful when arousal, not just blood flow, is the issue
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